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J Reconstr Microsurg
DOI: 10.1055/a-2616-4532
Original Article

Characterization of Soft Tissue Reconstruction Following Chordoma Resection

Shanmuga Priya Rajagopalan 
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Danielle Sim
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Waldemar A. Rodriguez-Silva
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Ananya Dewan
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Siam Rezwan
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Pritika Papali
2   Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Abdel-Hameed Al-Mistarehi
2   Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Andrew Hersh
2   Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Daniel Lubelski
2   Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Carisa M. Cooney   *
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
,
Salih Colakoglu   *
1   Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
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Abstract

Background

Chordomas are rare, malignant bone tumors of the axial skeleton. Soft tissue reconstruction is often needed postextirpation to reduce the risk of peritoneal content herniation. The purpose of this study is to describe presurgical factors associated with postchordoma resection reconstruction and evaluate postoperative outcomes.

Methods

We retrospectively reviewed patients who underwent reconstruction postexcision of chordomas derived from the lumbar or sacral regions at a single institution between 2012 and 2023. Wilcoxon rank sum test, chi-square test, Fisher's exact test, and Kruskal–Wallis test were used to compare outcomes based on reconstruction method.

Results

Among 68 patients who met the inclusion criteria, 67 underwent sacrectomy. Patients primarily received gluteus muscle (GM) flaps (n = 36, 53%). Vertical rectus abdominus myocutaneous (VRAM) and paraspinous muscle (PSM) flaps were the second most common, each used in 12 patients (18%). Eight patients (12%) underwent reconstruction with fasciocutaneous local flaps only. GM and VRAM flaps were primarily used to reconstruct defects at the level of the sacrum (n = 47, 98%) while PSM flaps were used for lumbar (n = 7 [58%]) and sacral (n = 5 [42%]) reconstruction, respectively. The median tumor volumes were 468 cm3 (271–1,592) for VRAM flaps, 92 cm3 (12–246) for GM flaps, 77 cm3 (34–239) for PSM flaps, and 25 cm3 (16–86) for non-muscle reconstruction; tumor volume was significantly greater in patients who underwent VRAM flap reconstruction. Median defect diameter managed by VRAM flaps was significantly longer compared with GM flaps (33 [30–46] cm vs. 22 [15–30] cm, respectively; p = 0.001). VRAM and PSM flap reconstruction were more often associated with hardware placement (p < 0.01). Median follow-up was 34 months. Neither reconstruction type nor hardware placement was associated with the incidence of postoperative complications.

Conclusion

We found that surgical reconstruction following chordoma resection varied depending on the chordoma spinal level, tumor volume, and defect diameter. Complication rates were similar among the included reconstructive options.

Keywords

soft tissue reconstruction - sacral chordoma - reconstructive algorithm

Note

This study was presented at the Plastic Surgery The Meeting (PSTM 2024); Northeastern Society of Plastic Surgeons (NESPS 2024).


* These senior authors contributed equally to this work.




Publication History

Received: 26 November 2024

Accepted: 07 May 2025

Article published online:
12 June 2025

© 2025. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 

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