Subscribe to RSS
DOI: 10.1055/s-0040-1720081
Electrochemical Organic Synthesis
#
Author Information
Prof. Hai-Chao Xu obtained a B.S. in Chemistry in 2006 from Xiamen University and a Ph.D. in Chemistry in 2010 from Washington University in St. Louis (USA) with Prof. Kevin D. Moeller. After postdoctoral work with Prof. Jonathan A. Ellman at Yale University (USA) from 2011 to 2013, he moved backed to Xiamen University to start his independent career. His research focuses on synthetic electrochemistry.
The potential of electrochemical organic synthesis in achieving sustainable and efficient chemical syntheses, while offering unique reactivity and selectivity, makes it a promising avenue for addressing the challenges in synthetic organic chemistry. The past two decades have witnessed a remarkable advancement in organic electrochemistry, primarily due to the influx of passionate and innovative scientists. These trailblazers, armed with their unique perspectives, are driving the field into uncharted territories, often surpassing the visions of the early pioneers. Their groundbreaking work is carving out new frontiers and making significant scientific impacts, which are aptly highlighted in this special issue. Their pioneering contributions are projected to extend the core foundation of electrochemistry and usher in transformative insights.
The articles featured in this special issue on electrochemical organic synthesis are the result of a diverse array of authors hailing from countries across the globe, including Brazil, Canada, China, France, Italy, Japan, Portugal, and the United States. This variety exemplifies the widespread adoption and universal appeal of electrochemistry in the realm of synthetic organic chemistry, confirming its global recognition and relevance within the international scientific community.
In this special issue, a selection of review papers vividly illuminates the latest advancements and emerging topics in electrochemical organic synthesis. He, Pan and colleagues explore the evolution of spirocyclic compound construction via electrochemical synthesis strategies since 2000.[1] Kong, Cao, and colleagues shed light on recent progress in electro-, photo-, and photoelectrochemical applications of quaternary ammonium salts.[2] Qin, Li and co-workers present an in-depth review of electrochemical difunctionalization of alkenes.[3] Lu and his team delve into transition-metal electrochemical asymmetric catalysis including the recently emerged photoelectrochemical asymmetric catalysis (PEAC).[4] Phillips, Pombeiro, and associates encapsulate the power of electrochemistry in catalytic enantioselective synthesis.[5] Zhang, Liu, and their team offer a comprehensive summary of electrochemical cascade cyclization reactions used in carbon ring and heterocycle production.[6] Mo and his team succinctly overview the latest breakthroughs in high-throughput experimentation technology for electrosynthesis.[7] Gui and his team have provided a comprehensive summary of halogen-mediated electrochemical transformations of sulfur-containing compounds.[8] Lastly, Chen and his team delve into the fascinating topic of photoelectrochemical cerium catalysis in their detailed review.[9]
Moreover, an assortment of research papers exhibits the cutting-edge methods and techniques in the field. A notable contribution from Charette, Poisson, Jubault, and their team delineates the synthesis of cyclopropylamines from the corresponding amides through a bromide-mediated, electro-induced Hofmann rearrangement.[10] Mitsudo, Suga and colleagues described a bromide-mediated electrochemical cross-coupling reaction between arylboronic esters and aryllithiums.[11] Zhang and associates presented a report on nickel-catalyzed electrochemical cyclizative carboxylation of alkene-tethered carbamoyl chlorides with atmospheric carbon dioxide.[12] Powers and his team provided electrochemical data for a collection of 70 aryl iodides.[13] Yang and Xia detailed an electrochemical alkylation reaction of buta-1,3-diene derivatives with alkyl halides.[14] Feng and his team presented the electrochemical esterification between aroylhydrazides and alcohols to yield structurally diverse carboxylic esters.[15] Brunetti, Bertuzzi, and Bandini provided a report on the electrochemical carboxylation of Morita–Baylis–Hillman (MBH) acetates with CO2.[16] Guo and his team reported a novel electrochemical reductive approach for the deoxygenation of alcohols.[17] Martins, Mendes, and their team reported an electrochemical synthesis of flavanones via oxa-Michael addition using a silver electrode as a sacrificial element.[18] Huang and his team reported an electrochemical method to synthesize 3-sulfonylindoles from o-alkynylanilines and sodium sulfinates.[19] Liu, Sun, and their colleagues demonstrated an electrochemical Ritter-type amidation of alkylarenes.[20] Fu, Cai and their team detailed an electrochemical method for vicinal difunctionalization of various alkenes with dibromomethane in alcohol for the synthesis of β-bromo-α-alkyloxyalkanes.[21] Liang, Xu, and Zeng, and co-workers reported catalyst-free electrochemical Minisci-type acylation reactions of heteroaromatic compounds.[22] Shida, Atobe, and their team reported on the electrocatalytic oxidation of cyclohexene performed in proton-exchange membrane (PEM) and anion-exchange membrane (AEM) electrolyzers.[23] Finally, Okada and his colleagues have reported their findings on radical cation [2+2] cycloadditions, made possible through surface-assisted pseudo-intramolecular electron transfers.[24]
As the guest editor, I have been deeply impressed by the quality, creativity, and enthusiasm of the researchers who have contributed to this special issue. We hope that this collection of articles will serve as a valuable resource for both newcomers and seasoned researchers in the field of electrochemical organic synthesis. Furthermore, we believe that the breakthroughs and challenges presented in this issue will inspire further research and innovation in this promising area of chemistry.
#
Conflict of Interest
The author declares no conflict of interest.
-
References
- 1 Wang Q, Liu H.-F, Ren S.-Y, He M.-X, Pan Y.-M. Synthesis 2023;
- 2 Chen X, Wang N.-Z, Cheng Y.-M, Kong X, Cao Z.-Y. Synthesis 2023;
- 3 Qin J.-H, Nan N, Li J.-H. Synthesis 2023;
- 4 Zheng W, Tao Y, Ma W, Lu Q. Synthesis 2023;
- 5 Faisca PhillipsA. M, Pombeiro AJ. L. Synthesis 2023;
- 6 Zhang C, Chen D, Wan J.-P, Liu Y. Synthesis 2023;
- 7 Chen H, Mo Y. Synthesis 2023;
- 8 Du J, Du Y.-l, Gui Q.-w. Synthesis 2023;
- 9 Wang Y, Liu S, Han J, Wang L, Chen J. Synthesis 2023;
- 10 Cantin T, Charette AB, Poisson T, Jubault P. Synthesis 2023;
- 11 Mitsudo K, Shigemori K, Shibata T, Mandai H, Sato E, Suga S. Synthesis 2023;
- 12 Wang L.-L, Liu X.-F, Wang H, Tao L, Huang J, Ren W.-M, Lu X.-B, Zhang W.-Z. Synthesis 2023;
- 13 Frey BL, Thai P, Patel L, Powers DC. Synthesis 2023;
- 14 Zhang H, Guo L, Yang C, Xia W. Synthesis 2023;
- 15 Xie P, Peng X, Feng P. Synthesis 2023;
- 16 Brunetti A, Bertuzzi G, Bandini M. Synthesis 2023;
- 17 Liu J, Li X, Chen X, Wang T, Xin L, Guo W. Synthesis 2023;
- 18 Santos WA. B, de Castro PP, Xavier FR, Braga AL, Martins GM, Mendes SR. Synthesis 2023;
- 19 Jiang P, Liu R, Meng X, Zheng B, Zheng Y, Huang S. Synthesis 2023;
- 20 Chu Q, Zhou Y, Ji C, Liu P, Sun P. Synthesis 2023;
- 21 Fu Z, Chen F, Hao G, Yi X, Zeng J, Cai H. Synthesis 2023;
- 22 Li Y, Liang S, Wang D, Xu K, Zeng C. Synthesis 2023;
- 23 Ido Y, Shimizu Y, Shida N, Atobe M. Synthesis 2023;
- 24 Adachi S, Maeta N, Nakayama K, Wang Z, Hashimoto Y, Okada Y. Synthesis 2023;
Publication History
Received: 03 August 2023
Accepted after revision: 03 August 2023
Article published online:
29 August 2023
© 2023. Thieme. All rights reserved
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Wang Q, Liu H.-F, Ren S.-Y, He M.-X, Pan Y.-M. Synthesis 2023;
- 2 Chen X, Wang N.-Z, Cheng Y.-M, Kong X, Cao Z.-Y. Synthesis 2023;
- 3 Qin J.-H, Nan N, Li J.-H. Synthesis 2023;
- 4 Zheng W, Tao Y, Ma W, Lu Q. Synthesis 2023;
- 5 Faisca PhillipsA. M, Pombeiro AJ. L. Synthesis 2023;
- 6 Zhang C, Chen D, Wan J.-P, Liu Y. Synthesis 2023;
- 7 Chen H, Mo Y. Synthesis 2023;
- 8 Du J, Du Y.-l, Gui Q.-w. Synthesis 2023;
- 9 Wang Y, Liu S, Han J, Wang L, Chen J. Synthesis 2023;
- 10 Cantin T, Charette AB, Poisson T, Jubault P. Synthesis 2023;
- 11 Mitsudo K, Shigemori K, Shibata T, Mandai H, Sato E, Suga S. Synthesis 2023;
- 12 Wang L.-L, Liu X.-F, Wang H, Tao L, Huang J, Ren W.-M, Lu X.-B, Zhang W.-Z. Synthesis 2023;
- 13 Frey BL, Thai P, Patel L, Powers DC. Synthesis 2023;
- 14 Zhang H, Guo L, Yang C, Xia W. Synthesis 2023;
- 15 Xie P, Peng X, Feng P. Synthesis 2023;
- 16 Brunetti A, Bertuzzi G, Bandini M. Synthesis 2023;
- 17 Liu J, Li X, Chen X, Wang T, Xin L, Guo W. Synthesis 2023;
- 18 Santos WA. B, de Castro PP, Xavier FR, Braga AL, Martins GM, Mendes SR. Synthesis 2023;
- 19 Jiang P, Liu R, Meng X, Zheng B, Zheng Y, Huang S. Synthesis 2023;
- 20 Chu Q, Zhou Y, Ji C, Liu P, Sun P. Synthesis 2023;
- 21 Fu Z, Chen F, Hao G, Yi X, Zeng J, Cai H. Synthesis 2023;
- 22 Li Y, Liang S, Wang D, Xu K, Zeng C. Synthesis 2023;
- 23 Ido Y, Shimizu Y, Shida N, Atobe M. Synthesis 2023;
- 24 Adachi S, Maeta N, Nakayama K, Wang Z, Hashimoto Y, Okada Y. Synthesis 2023;