Subscribe to RSS
DOI: 10.1055/s-0030-1256097
© Georg Thieme Verlag KG Stuttgart · New York
EUS-guided biliary drainage with placement of a new partially covered biliary stent for palliation of malignant biliary obstruction: a case series
Publication History
submitted 19 July 2010
accepted after revision 11 October 2010
Publication Date:
26 January 2011 (online)

Endoscopic ultrasonography-guided biliary drainage (EUS-BD) has been developed as an alternative drainage technique in patients with obstructive jaundice where endoscopic retrograde cholangiopancreatography (ERCP) has failed. Between July 2008 and December 2009, 16 patients (9 men; median age 79 years) with biliopancreatic malignancy, who were candidates for alternative techniques of biliary decompression because ERCP had been unsuccessful, underwent EUS-BD with placement of a transmural or transpapillary partially covered nitinol self-expandable metal stent (SEMS). EUS-assisted cholangiography was successful in all patients, with definition of the relevant anatomy, but biliary drainage was successfully performed in only 12 (75 %) of the 16 patients (9 choledochoduodenostomies with SEMS placement and 3 biliary rendezvous procedures with papillary SEMS placement), with regression of the cholestasis. No major complications and no procedure-related deaths occurred. There was one case of pneumoperitoneum which was managed conservatively. The median follow-up was 170 days. During the follow-up, eight patients of the 12 patients in whom biliary draining was successful died; four are currently alive. None of the patients required endoscopic reintervention. This series demonstrated that EUS-BD with a partially covered SEMS has a high rate of clinical success and low complication rates, and could represent an alternative choice for biliary decompression.
References
- 1 Williams E J, Taylor S, Fairclough P et al. Are we meeting the standards set for endoscopy? Results of a large scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice. Gut. 2007; 56 821-829
- 2 Varadarajulu S, Kilgore M L, Wilcox C M et al. Relationship among hospital ERCP volume, length of stay, and technical outcomes. Gastrointest Endosc. 2006; 64 338-347
- 3
Burmester E, Niehaus J, Leineweber T et al.
EUS-cholangio-drainage of the bile duct: report of 4 cases.
Gastrointest Endosc.
2003;
57
246-251
MissingFormLabel
- 4
Püspök A, Lomoschitz F, Dejaco C et al.
Endoscopic ultrasound guided therapy of benign and malignant biliary obstruction:
a case series.
Am J Gastroenterol.
2005;
100
1743-1747
MissingFormLabel
- 5
Kahaleh M, Hernandez A J, Tokar J et al.
Interventional EUS-guided cholangiography: evaluation of a technique in evolution.
Gastrointest Endosc.
2006;
64
52-59
MissingFormLabel
- 6
Itoi T, Itokawa F, Sofuni A et al.
Endoscopic ultrasound-guided choledochoduodenostomy in patients with failed endoscopic
retrograde cholangiopancreatography.
World J Gastroenterol.
2008;
14
6078-6082
MissingFormLabel
- 7 Tarantino I, Barresi L, Repici A et al. EUS-guided biliary drainage: a case series. Endoscopy. 2008; 40 336-339
- 8 Yamao K, Bhatia V, Mizuno N et al. EUS-guided choledochoduodenostomy for palliative biliary drainage in patients with malignant biliary obstruction: results of long-term follow-up. Endoscopy. 2008; 40 340-342
- 9
Maranki J, Hernandez A J, Arslan B et al.
Interventional endoscopic ultrasound-guided cholangiography: long-term experience
of an emerging alternative to percutaneous transhepatic cholangiography.
Endoscopy.
2009;
41
532-538
MissingFormLabel
- 10
Bories E, Pesenti C, Caillol F et al.
Transgastric endoscopic ultrasonography-guided biliary drainage: results of pilot
study.
Endoscopy.
2007;
39
287-291
MissingFormLabel
- 11
Will U, Thieme A, Fueldner F et al.
Treatment of biliary obstruction in selected patients by endoscopic ultrasonography
(EUS)-guided transluminal biliary drainage.
Endoscopy.
2007;
39
292-295
MissingFormLabel
- 12 Park do H, Koo J E, Oh J et al. EUS-guided biliary drainage with one-step placement of a fully covered metal stent for malignant biliary obstruction: a prospective feasibility study. Am J Gastroenterol. 2009; 104 2168-2174
- 13 Park D H, Song T J, Eum J et al. EUS-guided hepaticogastrostomy with a fully covered metal stent as the biliary diversion technique for an occluded biliary metal stent after a failed ERCP. Gastrointest Endosc. 2010; 71 413-419
- 14 Martins F P, Rossini L G, Ferrari A P. Migration of a covered metallic stent following endoscopic ultrasound-guided hepaticogastrostomy: fatal complication. Endoscopy.. 2010; 42 (Suppl. 2) E126-127
- 15 Moss A C, Morris E, Mac Mathuna P. Palliative biliary stents for obstructing pancreatic carcinoma. Cochrane Database Syst Rev. 2006; 19 2-CD004200
C. FabbriMD
Unit of Gastroenterology and Digestive Endoscopy
AUSL Bologna Bellaria-Maggiore Hospital
Largo Nigrisoli 2 40135 Bologna
Italy
Fax: +39-051-6225247
Email: carlo.fabbri@ausl.bologna.it